An Unsettled Debate About the Potential Role of Infection in Pathogenesis of Atherosclerosis

J Clin Med Res. 2017 Jul;9(7):547-554. doi: 10.14740/jocmr3032w. Epub 2017 May 22.

Abstract

Association of infection with atherosclerosis is by no means new. Several sero-epidemiological and pathologic studies as well as animal models have shown a link between infection and atherosclerosis. Exciting discoveries in recent times related to role of inter-individual genetic variation in modulating inflammatory response to infection have reignited the enthusiasm in proving a causal link between infection and atherosclerosis. The purpose of this article was to review and analyze the available evidence linking infection with atherosclerosis.

Keywords: Antibiotics; Inflammatory; Multifactorial.

Publication types

  • Review