Phytochemical investigation of Rumex thyrsiflorus Fingerh

Acta Biol Hung. 2017 Jun;68(2):232-236. doi: 10.1556/018.68.2017.2.10.

Abstract

In the course of our pharmacological screening of Polygonaceae species occurring in the Carpathian Basin the extracts prepared from the roots of Rumex thyrsiflorus showed promising antiproliferative, xanthine oxidase inhibitory and antibacterial activities. The present work deals with the isolation of compounds from the root of the plant. After multistep separation process, four compounds were obtained from the n-hexane, chloroform and ethyl acetate soluble fractions of the methanol extract of the root. The structures of the isolated compounds were determined as 1-palmitoylglycerol, β-sitosterol, (-)-epicatechin, and procyanidin B5.

Keywords: Polygonaceae; Rumex thyrsiflorus; phenolic compounds; procyanidin.

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Humans
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plant Roots / chemistry*
  • Rumex / chemistry*
  • Xanthine Oxidase / antagonists & inhibitors*

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents, Phytogenic
  • Enzyme Inhibitors
  • Plant Extracts
  • Xanthine Oxidase