Coccidioidomycosis: An underreported cause of death-Arizona, 2008-2013

Med Mycol. 2018 Feb 1;56(2):172-179. doi: 10.1093/mmy/myx041.

Abstract

In Arizona during 1997-2013, coccidioidomycosis increased from 21 to 90 cases/100,000 population, but coccidioidomycosis-associated deaths remained stable at 3-6 deaths/million population. We used the capture-recapture method by using death certificates and hospital discharge data to more fully estimate the total number of coccidioidomycosis-attributable deaths and compared this with published estimates. Death certificates were included if any cause of death included coccidioidomycosis; hospital discharge data deaths were included if any discharge diagnosis included coccidioidomycosis and laboratory confirmation. Among deaths during 2008-2013, we identified 529 coccidioidomycosis-attributable deaths from death certificates and 560 from hospital discharge data, with 251 deaths identified in both databases. Capture-recapture estimated 1,178 total coccidioidomycosis-attributable deaths, compared with 164 deaths (underlying cause of death) or 529 deaths (any cause of death) on death certificates. Coccidioidomycosis-attributable deaths are underreported from two- to sevenfold on Arizona death certificates, demonstrating an education need for death certifiers to document coccidioidomycosis mortality.

Keywords: capture-recapture; cause of death; coccidioidomycosis; epidemiology; surveillance.

MeSH terms

  • Arizona / epidemiology
  • Case-Control Studies
  • Cause of Death
  • Coccidioidomycosis / epidemiology*
  • Coccidioidomycosis / mortality*
  • Death Certificates
  • Disease Notification / statistics & numerical data
  • Humans
  • Medical Records