[Current topics in primary immune thrombocytopenia]

Rinsho Ketsueki. 2017;58(5):537-541. doi: 10.11406/rinketsu.58.537.
[Article in Japanese]

Abstract

Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by early platelet destruction due to antiplatelet autoantibodies. Recently, significant progress has been made regarding the pathophysiology of ITP. Nonetheless, the diagnosis of ITP in daily clinical practice is still based on differential diagnosis because of the lack of laboratory tests that can diagnose autoimmunity in ITP. In this chapter, the recent topics regarding the diagnosis and management of ITP have been reviewed.

Keywords: IPF%; Remission; Rituximab; Thrombopoietin.

MeSH terms

  • Humans
  • Immunologic Factors / therapeutic use
  • Practice Guidelines as Topic
  • Purpura, Thrombocytopenic, Idiopathic* / diagnosis
  • Purpura, Thrombocytopenic, Idiopathic* / drug therapy
  • Remission Induction
  • Rituximab / therapeutic use

Substances

  • Immunologic Factors
  • Rituximab