Pharmacological treatment of depression in geriatric chronic pain patients: a biopsychosocial approach integrating functional restoration

Expert Rev Clin Pharmacol. 2017 Sep;10(9):957-963. doi: 10.1080/17512433.2017.1339602. Epub 2017 Jun 14.

Abstract

A recent literature review concluded that the comorbidity of chronic pain and depression in adults is approximately 50%-65%. Physical and cognitive declines, concurrent multiple health conditions, and complex medication regimens add to the unique and complex challenges of effectively treating pain in particularly geriatric populations. Interdisciplinary medical intervention and monitoring for psychiatric sequelae, such as depression, cognitive change, and synergistic physical side effects are necessary. Areas covered: This review covers an extensive multi-database wide search of the pharmacotherapy of pain and depression in older adults, including biopsychosocial approaches. One of these, on which this review focuses, is Functional Restoration, an interdisciplinary application of quantified physical rehabilitation, case management, and cognitive behavioral and educational therapies to achieve improved well- being and better physical functioning. The biopsychosocial model incorporates an overview of the overlapping and interactive dimensions of a patient's life and addresses them within a comprehensive plan of treatment. Expert commentary: A multifactorial, rather than a single factor approach to the treatment of complicated health care problems such as chronic pain in an elderly patient is emphasized as an important change in perspective for the health care provider.

Keywords: Depression; biopsychosocial; chronic pain; elderly pain and depression; geriatric; pharmacotherapy.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Antidepressive Agents / therapeutic use
  • Chronic Pain / epidemiology
  • Chronic Pain / psychology*
  • Chronic Pain / therapy
  • Combined Modality Therapy
  • Depression / epidemiology
  • Depression / psychology
  • Depression / therapy*
  • Humans
  • Interdisciplinary Communication
  • Models, Psychological*

Substances

  • Antidepressive Agents