A survey of scientists' awareness of and attitudes to the use of human blood products and alternatives in human assisted reproductive technology

Hum Fertil (Camb). 2018 Sep;21(3):174-182. doi: 10.1080/14647273.2017.1334131. Epub 2017 Jun 7.

Abstract

Scientists working in assisted reproduction [members of Scientists in Reproductive Technology (SIRT) Australia, and subscribers of the online forums EmbryoMail and Quartec] were invited to complete an online questionnaire on the use of human blood products in assisted reproductive technologies (ART). A total of 260 started the questionnaire, with 208 (80%) completing it. A total of 62% of respondents had worked in human ART ≥8 years and 68% had post-graduate qualifications. The majority (82%) reported using products of animal or human origin, with 75% knowing why protein was added to culture media and 41% not worried by this. Almost half (49%) of respondents were unaware of regulations surrounding the use of human blood products in health care and 70% were unaware of adverse events involving human blood products in human ART. Most respondents (70%) indicated that they were not concerned about infections such as hepatitis, but agents such as prions were a cause for concern (57%). A total of 57% of respondents were unaware of alternatives, but 77% would use a suitable alternative. Using blood products in human ART is surrounded by a lack of awareness, often independent of respondents' qualifications or experience. A better understanding of these products and possible alternatives is required if informed decisions about their suitability are to be made.

Keywords: Assisted reproductive technologies; adverse event; blood products; culture media; human serum albumin.

MeSH terms

  • Animals
  • Attitude of Health Personnel*
  • Australia / epidemiology
  • Biomedical Research
  • Blood* / virology
  • Bloodless Medical and Surgical Procedures* / education
  • Cross Infection / etiology
  • Cross Infection / prevention & control*
  • Cross Infection / virology
  • Culture Media / adverse effects*
  • Culture Media / standards
  • Culture Media, Serum-Free / adverse effects
  • Culture Media, Serum-Free / standards
  • Female
  • Health Care Surveys
  • Health Knowledge, Attitudes, Practice*
  • Hepatitis / epidemiology
  • Hepatitis / etiology
  • Hepatitis / prevention & control
  • Humans
  • Internet
  • Male
  • Medical Laboratory Personnel / education
  • Needs Assessment
  • Prion Diseases / epidemiology
  • Prion Diseases / etiology
  • Prion Diseases / prevention & control
  • Prion Diseases / transmission
  • Reproductive Techniques, Assisted / adverse effects*
  • Reproductive Techniques, Assisted / standards
  • Risk
  • Serum Albumin, Human / adverse effects
  • Workforce

Substances

  • Culture Media
  • Culture Media, Serum-Free
  • Serum Albumin, Human