Cognitive functions: evaluation and changes after transcatheter aortic valve implantation in elderly patients

Future Cardiol. 2017 May;13(3):229-237. doi: 10.2217/fca-2016-0043. Epub 2017 Jun 6.

Abstract

Aim: To assess the prevalence and postprocedural evolution of cognitive impairment (CI) in patients undergoing transcatheter aortic valve implantation.

Methods: 62 patients were enrolled. Mini Mental state examination (MMSE), verbal memory test (VMT), visual search test (VST) and phonemic verbal fluency (PVF) were used to evaluate the cognitive status. CI was considered when a pathological result of MMSE was confirmed by VMT, VST and PVF.

Results: A total of 26.2% patients had CI at baseline. MMSE, VMT, VST and PVF were pathologic in 39, 16.1, 8.1 and 22.6% of the patients, respectively. Overall, no significant differences in cognitive function in any dimension were observed from baseline up to 1-year follow-up.

Conclusion: CI is frequent in patients undergoing transcatheter aortic valve implantation, though the procedure does not forge cognitive status.

Keywords: Mini Mental state examination; aortic stenosis; cognitive impairment; cognitive status; geriatric evaluation; multidimensional; quality of life; transcatheter aortic valve implantation.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aortic Valve / surgery*
  • Aortic Valve Stenosis / surgery*
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / etiology
  • Cognition*
  • Female
  • Heart Valve Prosthesis Implantation
  • Humans
  • Male
  • Memory Disorders / diagnosis
  • Memory Disorders / etiology
  • Mental Status and Dementia Tests
  • Pilot Projects
  • Transcatheter Aortic Valve Replacement / adverse effects*
  • Treatment Outcome