Keywords: ER, estrogen receptor; MSK-IMPACT; MSK-IMPACT, Memorial Sloan Kettering–Integrated Mutation Profiling of Actionable Cancer Targets; PET, positron emission tomography; PR, progesterone receptor; adenocarcinoma; adnexal; apocrine; cytotoxic chemotherapy; immunohistochemistry; metastatic; multidisciplinary; radiation; skin cancer.