Intracranial Infectious and Inflammatory Diseases Presenting as Neurosurgical Pathologies

Neurosurgery. 2017 Jul 1;81(1):10-28. doi: 10.1093/neuros/nyx201.

Abstract

There are many infectious and inflammatory processes affecting the central nervous system that can simulate other neurosurgical pathologies (e.g. tumor) and may precipitate a brain biopsy for definitive diagnosis if not suspected a priori. The challenge for the healthcare team is to recognize imaging features that support a nonsurgical pathology to avoid unnecessary interventions. This review aims to give a general overview of some common inflammatory and infectious entities that affect the central nervous system, with illustrative examples and highlighting important pearls and pitfalls.

Keywords: Amebic encephalitis; Amyloid angiopathy-related inflammation; Cerebral abscess; Demyelination; Empyema; Neurocysticercosis; Neurosyphilis; Toxoplasmosis; Tuberculosis; Vasculitis.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Brain Diseases / diagnostic imaging*
  • Brain Diseases / etiology
  • Brain Diseases / surgery*
  • Humans
  • Magnetic Resonance Imaging
  • Neuroradiography