Imaging of haemophilic arthropathy in growing joints: pitfalls in ultrasound and MRI

M Soliman; P Daruge; S S J Dertkigil; E De Avila Fernandes; J R Negrao; S de Aguiar Vilela Mitraud; E T I Sakuma; A R C Fernandes; N Zhang; A Huo; Y-J Li; F Zhou; B M Rodrigues; A Mohanta; V S Blanchette; A S Doria

doi:10.1111/hae.13249

Imaging of haemophilic arthropathy in growing joints: pitfalls in ultrasound and MRI

Haemophilia. 2017 Sep;23(5):660-672. doi: 10.1111/hae.13249. Epub 2017 Jun 2.

Authors

M Soliman^{1

2}, P Daruge³, S S J Dertkigil⁴, E De Avila Fernandes⁵, J R Negrao⁵, S de Aguiar Vilela Mitraud⁵, E T I Sakuma⁴, A R C Fernandes⁵, N Zhang⁶, A Huo⁶, Y-J Li⁷, F Zhou⁷, B M Rodrigues³, A Mohanta^{1

2}, V S Blanchette⁸, A S Doria^{1

2}

Affiliations

¹ Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
² Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
³ Institute of Radiology, Universidade de Sao Paulo (USP), Sao Paulo, SP, Brazil.
⁴ Department of Radiology, Universidade de Campinas (UNICAMP), Campinas, SP, Brazil.
⁵ Department of Radiology, Universidade de Federal de Sao Paulo (UNIFESP), Sao Paulo, SP, Brazil.
⁶ Department of Radiology, Beijing Children's Hospital, Beijing, China.
⁷ Department of Radiology, Nanfang Hospital, Guangzhou, China.
⁸ Department of Hematology & Oncology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

PMID: 28574216
DOI: 10.1111/hae.13249

Abstract

The purpose of this review was to summarize the current knowledge on the utilization of magnetic resonance imaging (MRI) and ultrasound (US) for assessing arthropathy in children and adolescents with haemophilia and to recognize the limitations of each imaging modality and pitfalls in the diagnosis of soft tissue and osteochondral abnormalities. Awareness of MRI and US limitations and pitfalls in the assessment of joints in persons with haemophilia is essential for accurate diagnosis and optimal management of haemophilic arthropathy.

Keywords: children; growing joints; haemophilic arthropathy; imaging; magnetic resonance imaging; ultrasound.

Publication types

Review

MeSH terms

Hemarthrosis / diagnostic imaging*
Hemarthrosis / etiology*
Hemarthrosis / pathology
Hemophilia A / complications*
Hemophilia B / complications*
Humans
Image Interpretation, Computer-Assisted
Magnetic Resonance Imaging / standards
Reproducibility of Results
Sensitivity and Specificity
Severity of Illness Index
Ultrasonography / standards