Optimising Intravenous Volume Resuscitation of the Newborn in the Delivery Room: Practical Considerations and Gaps in Knowledge

Neonatology. 2017;112(2):163-171. doi: 10.1159/000475456. Epub 2017 Jun 2.

Abstract

Volume resuscitation (VR) for the treatment of newborn shock is a rare but potentially lifesaving intervention. Conducting clinical studies to assess the effectiveness of VR in the delivery room during newborn stabilization is challenging. We review the available literature and current management guidelines to determine which infants will benefit from VR, the frequency of VR, and the choice of agents used. In addition, the potential role for placental transfusion in the prevention of newborn shock is explored.

Keywords: Asphyxia; Cord blood; Delivery; Neonatal haemodynamics; Newborn resuscitation; Shock.

Publication types

  • Review

MeSH terms

  • Asphyxia Neonatorum / diagnosis
  • Asphyxia Neonatorum / mortality
  • Asphyxia Neonatorum / physiopathology
  • Asphyxia Neonatorum / therapy*
  • Blood Substitutes / administration & dosage*
  • Blood Substitutes / adverse effects
  • Blood Transfusion / methods*
  • Clinical Decision-Making
  • Delivery Rooms*
  • Fluid Therapy / adverse effects
  • Fluid Therapy / methods*
  • Hemodynamics
  • Humans
  • Infant, Newborn
  • Infusions, Intravenous
  • Neonatology / methods*
  • Patient Selection
  • Recovery of Function
  • Resuscitation / adverse effects
  • Resuscitation / methods*
  • Risk Factors
  • Shock / diagnosis
  • Shock / mortality
  • Shock / physiopathology
  • Shock / therapy*
  • Treatment Outcome

Substances

  • Blood Substitutes