Varicella associated pneumoniae in a pediatric population

Ital J Pediatr. 2017 May 30;43(1):49. doi: 10.1186/s13052-017-0366-8.

Abstract

Background: Varicella pneumonia has been studied extensively in adults; it may also affect children and may require hospitalization.

Methods: We examined pneumonia complications in children hospitalized for varicella, over a 13 year period.

Results: Pneumonia occurred in 8.2% of children hospitalized for varicella. The median length of hospitalization was 6 days. No statistically significant difference in length of stay was detected between immunodepressed children and previously healthy children. The hospitalization was on average shorter in patients who started antiviral therapy within 24 h of varicella onset. None of the included patients had been previously immunized for varicella.

Conclusions: Our results support the need for increased awareness of current varicella prevention recommendations among both immunocompetent and immunodepressed individuals. In children affected by varicella, prompt antiviral therapy may be indicated to reduce the number of days of hospitalization.

Keywords: Varicella; children; hospitalization; pneumoniae complication; vaccine.

MeSH terms

  • Adolescent
  • Age Distribution
  • Chickenpox / diagnosis
  • Chickenpox / epidemiology*
  • Chickenpox / therapy
  • Chickenpox Vaccine / administration & dosage*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Comorbidity
  • Female
  • Hospitalization / statistics & numerical data
  • Hospitals, Pediatric
  • Humans
  • Incidence
  • Italy / epidemiology
  • Male
  • Pneumonia, Viral / diagnosis*
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / therapy
  • Prognosis
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Sex Distribution
  • Vaccination / standards
  • Vaccination / trends

Substances

  • Chickenpox Vaccine