Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF79_0107) Identified from Shanxi, China

AIDS Res Hum Retroviruses. 2017 Oct;33(10):1056-1060. doi: 10.1089/aid.2017.0066. Epub 2017 May 30.

Abstract

We report a novel HIV-1 circulating recombinant form (CRF79_0107) from three epidemiologically unlinked patients through sexual contact in Shanxi province of China. This is the first second-generation circulating recombinant form identified in China. The breakpoint analysis of recombinants showed that CRF79_0107 was composed of CRF01_AE and CRF07_BC, with three CRF07_BC segments inserted into the CRF01_AE backbone. The emergence of CRF79_0107 increases the complexity of the HIV epidemic in China.

Keywords: CRF79_0107; China; Shanxi.

MeSH terms

  • Adult
  • Base Sequence
  • China / epidemiology
  • Genetic Variation / genetics
  • Genome, Viral / genetics*
  • HIV Infections / epidemiology*
  • HIV Infections / virology
  • HIV-1 / classification
  • HIV-1 / genetics*
  • Humans
  • Male
  • Middle Aged
  • RNA, Viral / blood
  • RNA, Viral / genetics*
  • Sequence Analysis, RNA
  • Sexual Behavior
  • Sexual Partners
  • Sexual and Gender Minorities

Substances

  • RNA, Viral