Polyarteritis nodosa (PAN) is a necrotizing vasculitis that has been associated with viral infections, especially hepatitis B virus. We hereby report a case of tissue-invasive cytomegalovirus (CMV)-induced PAN in a liver transplant recipient presenting with acute kidney injury and active urinary sediment. Treatment directed against both PAN and CMV resulted in improvement in kidney function, normalization of urinary indices and resolution of the CMV infection. There was no recurrence of either PAN or CMV after a 3-year follow-up period.
Keywords: clinical research/practice; infection and infectious agents; infectious disease; liver disease: infectious; liver transplantation/hepatology; vasculopathy; viral: Cytomegalovirus (CMV).
© 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.