Safety issues associated with the use of nanoparticles in human body

Photodiagnosis Photodyn Ther. 2017 Sep:19:67-72. doi: 10.1016/j.pdpdt.2017.05.012. Epub 2017 May 24.

Abstract

Nanotechnology has transformed the world by the introduction of a distinctive class of materials and products in a wide array of fields. It has contributed to the production of innovative materials and devices. Having unique advantages and domestic along with industrial applications, however, has raised the issue of safety for consumers, producers and environment. Having a comparative smaller dimension and other exclusive properties, nanoparticles have the ability to harm human body by interacting through various mechanisms. Here, we endeavoured to review and discuss the characteristics of nanoparticles relevant to their toxicity, conceivable exposure routes of nanoparticles to human body like skin contact, inhalation, and ingestion, and the basic approaches which can aid to control human exposures to toxic nanoparticles have been discussed.

Keywords: Human body; Nanotechnology; Safety; Toxicity, Photodynamic Therapy.

Publication types

  • Review

MeSH terms

  • Drug Administration Routes
  • Drug Stability
  • Humans
  • Hydrazones
  • Nanoparticles / chemistry
  • Nanoparticles / metabolism
  • Nanoparticles / toxicity*
  • Particle Size
  • Pharmacokinetics
  • Polymers

Substances

  • Hydrazones
  • Polymers
  • carbonyl 3-chlorophenylhydrazone