Comparison of apparent diffusion coefficient in diffusion-weighted magnetic resonance imaging and morphological assessment of breast tumors

Pol J Pathol. 2016;67(4):398-403. doi: 10.5114/pjp.2016.65874.

Abstract

The aim of the study was to assess the relationship between the apparent diffusion coefficient in diffusion-weighted magnetic (DWM) resonance imaging (MRI) and selected morphological parameters of the breast lesions. Diffusion-weighted imaging data and the pathology reports of 160 women treated surgically between January 2011 and March 2015 were analyzed. When classified, 107 invasive carcinomas, 13 pre-invasive carcinomas and 40 benign lesions were identified. The mean apparent diffusion coefficient was significantly lower for invasive carcinomas than benign lesions of the breast (0.87 ±0.02 vs. 1.58 ±0.04; p < 0.001). What is more there was an inverse correlation between value of apparent diffusion coefficient in diffusion-weighted magnetic resonance imaging and the grade of breast carcinomas (p = 0.04).

Keywords: MRI; diffuse coefficient in DWM; tumor grade; breast cancer.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / diagnostic imaging*
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Humans
  • Middle Aged
  • Young Adult