Immunotherapy of Recurrent Herpes Labialis With Squaric Acid

JAMA Dermatol. 2017 Aug 1;153(8):828-829. doi: 10.1001/jamadermatol.2017.0725.

Authors

Maria Alora Palli^{1

2}, Hugh McTavish³, Alexa Kimball^{2

4}, Thomas D Horn^{1

2

3}

Affiliations

¹ Department of Dermatology, Massachusetts General Hospital, Boston.
² Harvard Medical School, Boston, Massachusetts.
³ Squarex, LLC, Pine Springs, Minnesota.
⁴ Beth Israel Deaconess Medical Center, Boston, Massachusetts.

Abstract

This randomized placebo-controlled study examines the results of squaric acid dibutyl ester for the treatment of herpes labialis in adults.

Publication types

Randomized Controlled Trial

MeSH terms

Administration, Topical
Adolescent
Adult
Aged
Cyclobutanes / administration & dosage*
Dose-Response Relationship, Drug
Double-Blind Method
Female
Herpes Labialis / diagnosis
Herpes Labialis / drug therapy*
Humans
Immunotherapy / methods*
Male
Middle Aged
Recurrence
Retrospective Studies
Treatment Outcome
Young Adult

Substances

Cyclobutanes
squaric acid