Electrophoretic deposition of organic/inorganic composite coatings containing ZnO nanoparticles exhibiting antibacterial properties

Joanna Karbowniczek; Luis Cordero-Arias; Sannakaisa Virtanen; Superb K Misra; Eugenia Valsami-Jones; Lorena Tuchscherr; Bogdan Rutkowski; Kamil Górecki; Piotr Bała; Aleksandra Czyrska-Filemonowicz; Aldo R Boccaccini

doi:10.1016/j.msec.2017.03.180

Electrophoretic deposition of organic/inorganic composite coatings containing ZnO nanoparticles exhibiting antibacterial properties

Mater Sci Eng C Mater Biol Appl. 2017 Aug 1:77:780-789. doi: 10.1016/j.msec.2017.03.180. Epub 2017 Mar 22.

Affiliations

¹ Faculty of Metals Engineering and Industrial Computer Science, AGH University of Science and Technology, Al. A. Mickiewicza 30, PL-30059 Krakow, Poland.
² Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstrasse 6, D-91058 Erlangen, Germany; Escuela de Ciencia e Ingeniería de los Materiales (ECIM), Costa Rican Institute of Technology (ITCR), Cartago 159-7050, Costa Rica.
³ Institute for Surface Science and Corrosion, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Martensstrasse 7, D-91058 Erlangen, Germany.
⁴ Materials Science and Engineering, Indian Institute of Technology-Gandhinagar, India.
⁵ School of Geography, Earth and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
⁶ Institute of Medical Microbiology, Jena University Hospital, Jena, Germany.
⁷ Faculty of Metals Engineering and Industrial Computer Science, AGH University of Science and Technology, Al. A. Mickiewicza 30, PL-30059 Krakow, Poland; Academic Centre for Materials and Nanotechnology, AGH University of Science and Technology, Al. A. Mickiewicza 30, PL-30059, Krakow, Poland.
⁸ Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstrasse 6, D-91058 Erlangen, Germany. Electronic address: aldo.boccaccini@ww.uni-erlangen.de.

PMID: 28532093
DOI: 10.1016/j.msec.2017.03.180

Abstract

To address one of the serious problems associated with permanent implants, namely bacterial infections, novel organic/inorganic coatings containing zinc oxide nanoparticles (nZnO) are proposed. Coatings were obtained by electrophoretic deposition (EPD) on stainless steel 316L. Different deposition conditions namely: deposition times in the range 60-300s and applied voltage in the range 5-30V as well as developing a layered coating approach were studied. Antibacterial tests against gram-positive Staphylococcus aureus and gram-negative Salmonella enteric bacteria confirmed the activity of nZnO to prevent bacterial growth. Coatings composition and morphology were analyzed by thermogravimetric analysis, Fourier transform infrared spectroscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy. Moreover, the corrosion resistance was analyzed by evaluation of the polarization curves in DMEM at 37°C, and it was found that coatings containing nZnO increased the corrosion resistance compared to the bare substrate. Considering all results, the newly developed coatings represent a suitable alternative for the surface modification of metallic implants.

Keywords: Antibacterial surfaces; Bioactive glass; Chitosan; Coatings; Electrophoretic deposition; ZnO nanoparticles.

MeSH terms

Anti-Bacterial Agents
Chitosan
Coated Materials, Biocompatible
Durapatite
Metal Nanoparticles*
Staphylococcus aureus
Zinc Oxide

Substances

Anti-Bacterial Agents
Coated Materials, Biocompatible
Chitosan
Durapatite
Zinc Oxide