Applications of Gold Nanoparticles in Nanomedicine: Recent Advances in Vaccines

Molecules. 2017 May 22;22(5):857. doi: 10.3390/molecules22050857.

Abstract

Nowadays, gold is used in (nano-)medicine, usually in the form of nanoparticles, due to the solid proofs given of its therapeutic effects on several diseases. Gold also plays an important role in the vaccine field as an adjuvant and a carrier, reducing toxicity, enhancing immunogenic activity, and providing stability in storage. An even brighter golden future is expected for gold applications in this area.

Keywords: AIDS; cancer; gold nanoparticles; hepatitis B; nanomedicine; vaccines.

Publication types

  • Review

MeSH terms

  • AIDS Vaccines / administration & dosage*
  • AIDS Vaccines / biosynthesis
  • Acquired Immunodeficiency Syndrome / immunology
  • Acquired Immunodeficiency Syndrome / pathology
  • Acquired Immunodeficiency Syndrome / prevention & control
  • Adjuvants, Immunologic / administration & dosage
  • Cancer Vaccines / administration & dosage*
  • Cancer Vaccines / biosynthesis
  • Gold / administration & dosage
  • Gold / immunology*
  • Hepatitis B / immunology
  • Hepatitis B / pathology
  • Hepatitis B / prevention & control
  • Hepatitis B Vaccines / administration & dosage*
  • Hepatitis B Vaccines / biosynthesis
  • Humans
  • Metal Nanoparticles / administration & dosage*
  • Metal Nanoparticles / chemistry
  • Nanomedicine / methods
  • Nanomedicine / trends*
  • Neoplasms / immunology
  • Neoplasms / pathology
  • Neoplasms / prevention & control

Substances

  • AIDS Vaccines
  • Adjuvants, Immunologic
  • Cancer Vaccines
  • Hepatitis B Vaccines
  • Gold