A Colorimetric Fluorescent Probe for SO2 Derivatives-Bisulfite and Sulfite at Nanomolar Level

J Fluoresc. 2017 Sep;27(5):1767-1775. doi: 10.1007/s10895-017-2115-1. Epub 2017 May 21.

Abstract

A colorimetric fluorescent probe with fluorescence emission feature sensitive to SO2 derivatives, i.e. bisulfite (HSO3-) and sulfite (SO32-), was developed based on the HSO3-/SO32--mediated nucleophilic addition reaction of the probe that. This probe exhibited SO32- sensing ability with detection limit down to 46 nM and desired selectivity over other reference anions and redox species. The preliminary fluorescence bioimaging experiments have validated the practicability of the as-prepared probe for SO2 derivatives sensing in living cells.

Keywords: Bioimaging; Fluorescent probe; Sulfur dioxide derivatives.

MeSH terms

  • Carbocyanines / chemistry*
  • Colorimetry / methods*
  • Fluorescence
  • Fluorescent Dyes / chemistry*
  • Humans
  • Limit of Detection
  • MCF-7 Cells
  • Oxazines / chemistry*
  • Quinolines / chemistry*
  • Sulfites / analysis*
  • Sulfur Dioxide / analysis*

Substances

  • 7-hydroxy-(8-oxazine-2-one)-quinoline
  • Carbocyanines
  • Fluorescent Dyes
  • Oxazines
  • Quinolines
  • Sulfites
  • tetramethylene hemicyanine
  • Sulfur Dioxide
  • hydrogen sulfite