Saposhnikoviae divaricata: a phytochemical, pharmacological, and pharmacokinetic review

Chin J Nat Med. 2017 Apr;15(4):255-264. doi: 10.1016/S1875-5364(17)30042-0.

Abstract

Saposhnikoviae divaricata (Turcz.) Schischk (SD) is a traditional Chinese herb commonly used to treat clinical conditions such as rheumatism and allergic rhinitis. This review article evaluates a collection of works on in vitro and biochemical studies of SD. The discourse on the diverse class of chromones and coumarins in SD offers an insight to the pharmacological effects of these bioactive constituents as anti-inflammatory, analgesic, immunoregulatory, antioxidative, and anti-proliferative agents. It is highlighted that there is a structural relationship between the constituents and bioactive activities, which in effect provides a valid reasoning and reaffirm the use of SD in the treatment of the pathologies in Chinese medicine.

Keywords: Analgesic; Anti-inflammatory; Anti-proliferative; Chinese herbal medicine; Immunomodulatory; Saposhnikoviae divaricata.

Publication types

  • Review

MeSH terms

  • Animals
  • Apiaceae / chemistry*
  • Drugs, Chinese Herbal* / chemistry
  • Drugs, Chinese Herbal* / pharmacokinetics
  • Drugs, Chinese Herbal* / pharmacology
  • Humans

Substances

  • Drugs, Chinese Herbal