This paper presents a bio-inspired adaptive micro-lens with electrically tunable focus made of non-ionic high-molecular-weight polyvinyl chloride (PVC) gel. The optical device mimics the design of the crystalline lens and ciliary muscle of the human eye. It consists of a plano-convex PVC gel micro-lens on Indium Tin Oxide (ITO) glass, confined with an annular electrode operating as an artificial ciliary muscle. Upon electrical activation, the electroactive adhesive force of the PVC gel is exerted on the annular anode electrode, which reduces the sagittal height of the plano-convex PVC gel lens, resulting in focal length variation of the micro-lens. The focal length increases from 3.8 mm to 22.3 mm as the applied field is varied from 200 V/mm to 800 V/mm, comparable to that of the human lens. The device combines excellent optical characteristics with structural simplicity, fast response speed, silent operation, and low power consumption. The results show the PVC gel micro-lens is expected to open up new perspectives on practical tunable optics.