Fibroelastic pseudotumor elastofibroma dorsi detected by 18F-FDG PET/CT scan and by postherapy radioiodine SPECT/CT
Rev Esp Med Nucl Imagen Mol (Engl Ed). 2018 Jan-Feb;37(1):46-49.
doi: 10.1016/j.remn.2017.02.012.
Epub 2017 May 16.
[Article in
English,
Spanish]
Affiliations
- 1 Servicio de Medicina Nuclear, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España. Electronic address: magdalena.oporto@ssib.es.
- 2 Servicio de Medicina Nuclear, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España.
- 3 Servicio de Medicina Nuclear, Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, España; Instituto de Investigación Sanitaria de Palma, Palma de Mallorca, Islas Baleares, España.
Abstract
Radioiodine uptake in the thyroid tissue, metastasis of differentiated thyroid cancer (DTC), and in other tissues, depends on the expression of sodium-iodide symporter (NIS). Vascular permeability, effusions, inflammation, and other mechanisms may also play a role in the accumulation of radioactive iodine. A 63-year-old woman underwent radioiodine therapy, as well as a post-therapy whole-body scan, as she was suspected of having lung metastasis from thyroid carcinoma. The scan not only showed uptake at the lung metastasis but also a faint diffuse bilateral uptake in the posterior thorax. On SPECT/CT this uptake was located in a known Elastofibroma Dorsi (ED) previously diagnosed by contrast CT and viewed in a FDG PET/CT. The radioiodine uptake in ED, especially if typical, is not a diagnostic problem in SPECT/CT study, but can be misleading in a study limited to a few planar images, particularly if the uptake occurs asymmetrically, or ED is located in a unsuspected area.
Keywords:
(131)I SPECT/TC; Carcinoma diferenciado de tiroides; Differentiated thyroid cancer; Elastofibroma dorsi; False positive scan; Falso positivo scan; I-131 SPECT/CT; Radioiodine; Radioyodo.
Copyright © 2017 Elsevier España, S.L.U. y SEMNIM. All rights reserved.
MeSH terms
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Carcinoma, Papillary / radiotherapy
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Carcinoma, Papillary / secondary
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Diagnosis, Differential
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Female
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Fibroma / diagnostic imaging*
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Fibroma / metabolism
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Fluorine Radioisotopes / pharmacokinetics*
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Fluorodeoxyglucose F18 / pharmacokinetics*
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Humans
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Iodine Radioisotopes / pharmacokinetics
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Iodine Radioisotopes / therapeutic use
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Lung Neoplasms / radiotherapy
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Lung Neoplasms / secondary
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Middle Aged
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Positron Emission Tomography Computed Tomography*
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Radionuclide Imaging
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Radiopharmaceuticals / pharmacokinetics*
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Radiopharmaceuticals / therapeutic use
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Radiotherapy, Adjuvant
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Single Photon Emission Computed Tomography Computed Tomography*
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Solitary Pulmonary Nodule / diagnostic imaging
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Thoracic Neoplasms / diagnostic imaging*
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Thoracic Neoplasms / metabolism
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Thoracic Neoplasms / secondary
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Thyroid Neoplasms / radiotherapy
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Tissue Distribution
Substances
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Fluorine Radioisotopes
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Iodine Radioisotopes
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Radiopharmaceuticals
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Fluorodeoxyglucose F18
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Fluorine-18