Advances in medical imaging for the diagnosis and management of common genitourinary cancers

Urol Oncol. 2017 Jul;35(7):473-491. doi: 10.1016/j.urolonc.2017.04.014. Epub 2017 May 12.

Abstract

Medical imaging of the 3 most common genitourinary (GU) cancers-prostate adenocarcinoma, renal cell carcinoma, and urothelial carcinoma of the bladder-has evolved significantly during the last decades. The most commonly used imaging modalities for the diagnosis, staging, and follow-up of GU cancers are computed tomography, magnetic resonance imaging (MRI), and positron emission tomography (PET). Multiplanar multidetector computed tomography and multiparametric MRI with diffusion-weighted imaging are the main imaging modalities for renal cell carcinoma and urothelial carcinoma, and although multiparametric MRI is rapidly becoming the main imaging tool in the evaluation of prostate adenocarcinoma, biopsy is still required for diagnosis. Functional and molecular imaging using 18-fluorodeoxyglucose-PET and sodium fluoride-PET are essential for the diagnosis, and especially follow-up, of metastatic GU tumors. This review provides an overview of the latest advances in the imaging of these 3 major GU cancers.

Keywords: Bladder urothelial carcinoma; CT; MRI; PET; Prostate adenocarcinoma; Renal cell carcinoma.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Positron-Emission Tomography / methods*
  • Urogenital Neoplasms / diagnosis*
  • Urogenital Neoplasms / diagnostic imaging*
  • Urogenital Neoplasms / therapy