Alcohol-Related Dementia: A Systemic Review of Epidemiological Studies

Psychosomatics. 2017 Jul-Aug;58(4):331-342. doi: 10.1016/j.psym.2017.02.012. Epub 2017 Mar 1.

Abstract

Background: Alcohol-related dementia (ARD) is a heterogeneous long-term cognitive problem that can develop in the course of alcoholism. Current understanding of ARD remains limited.

Methods: We conducted a systematic review to synthesize available data on the epidemiology of ARD, through searching the relevant studies in the PubMed, PsycINFO, and ALOIS. "Alcohol" and "dementia" were used as keywords.

Results: We included articles published between January 1, 1991 and February 29, 2016, where language was not limited. Of the 9 identified articles, the prevalence of ARD ranged from 1.19/1000 in multiday admission patients residing in the United Kingdom to 25.6% in elderly clinic alcoholics from the United States. The proportion of ARD in early-onset dementia taken from 3 studies was approximately 10%, whereas only 1.28% in late-onset dementia taken from 1 study.

Conclusions: Considering the relatively high proportion of ARD in early-onset dementia and its potentially reversible course, future investigation into ARD is necessary.

Keywords: Alcohol; Alcohol-related dementia; Cognition; Dementia; Health insurance research database.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Alcoholism / complications*
  • Dementia / etiology*
  • Epidemiologic Studies*
  • Humans
  • Neuropsychological Tests