Alteration of serum adropin level in preeclampsia

Pregnancy Hypertens. 2017 Apr:8:6-8. doi: 10.1016/j.preghy.2017.02.003. Epub 2017 Mar 1.

Abstract

To clarify the alterations in serum adropin and preptin concentrations in preeclampsia, we determined serum adropin and preptin levels in 29 women with normal pregnancy and 32 women with preeclampsia. We found that maternal age, body mass index and fetal gender were not significantly different between two groups; however, blood pressure, gestational age and neonatal birth weight were significantly different. Serum adropin levels were significantly increased in women with preeclampsia compared with those with normal pregnancy but there were no significant differences in preptin levels. An increase in maternal serum adropin level was found in preeclampsia, and this may be a compensation for pregnancy complicated with preeclampsia.

Keywords: Adropin; Preeclampsia; Pregnancy; Preptin.

MeSH terms

  • Adult
  • Biomarkers / blood
  • Birth Weight
  • Blood Pressure
  • Blood Proteins
  • Case-Control Studies
  • Cross-Sectional Studies
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Insulin-Like Growth Factor II
  • Intercellular Signaling Peptides and Proteins
  • Male
  • Peptide Fragments / blood
  • Peptides / blood*
  • Pre-Eclampsia / blood*
  • Pre-Eclampsia / diagnosis
  • Pre-Eclampsia / physiopathology
  • Pregnancy
  • Up-Regulation

Substances

  • Biomarkers
  • Blood Proteins
  • Enho protein, human
  • Intercellular Signaling Peptides and Proteins
  • Peptide Fragments
  • Peptides
  • preptin
  • Insulin-Like Growth Factor II