Imaging of IgG4-related disease of the head and neck

A Thompson; A Whyte

doi:10.1016/j.crad.2017.04.004

Imaging of IgG4-related disease of the head and neck

Clin Radiol. 2018 Jan;73(1):106-120. doi: 10.1016/j.crad.2017.04.004. Epub 2017 May 10.

Authors

A Thompson¹, A Whyte²

Affiliations

¹ Neurological Intervention and Imaging Service Western Australia, Level 1, G Block, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia; Neurological Intervention and Imaging Service Western Australia, Royal Perth Hospital, 197 Wellington Street, Perth, WA 6000, Australia; Princess Margaret Hospital for Children, Roberts Road, Subiaco, WA 6008, Australia. Electronic address: andrew.thompson2@health.wa.gov.au.
² Perth Radiological Clinic, 127 Hamersley Road, Subiaco, WA 6008, Australia; School of Surgery, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia; Department of Medicine and Radiology, University of Melbourne, Parkville, VIC 3010, Australia.

PMID: 28501095
DOI: 10.1016/j.crad.2017.04.004

Abstract

IgG4-related disease is a systemic, inflammatory disorder typically involving multiple organ systems. Several eponymous conditions described previously in the clinical and radiology literature are now recognised to be part of the IgG4-related disease spectrum. This includes multiple manifestations in the head and neck region, which are the subject of this review. Imaging can occasionally suggest the specific diagnosis of IgG4 disease. More commonly, it will be included in a limited differential diagnosis that requires clarification with the aid of image-guided biopsy. There are strict histopathological criteria for the diagnosis of IgG4-related disease.

Publication types

Review

MeSH terms

Autoimmune Diseases / diagnostic imaging*
Diagnostic Imaging / methods*
Head / diagnostic imaging
Humans
Immunoglobulin G
Neck / diagnostic imaging
Salivary Gland Diseases / diagnostic imaging*

Substances

Immunoglobulin G