Bio-templated silica composites for next-generation biomedical applications

Karunya Albert; Xin-Chun Huang; Hsin-Yun Hsu

doi:10.1016/j.cis.2017.04.011

Bio-templated silica composites for next-generation biomedical applications

Adv Colloid Interface Sci. 2017 Nov:249:272-289. doi: 10.1016/j.cis.2017.04.011. Epub 2017 Apr 29.

Authors

Karunya Albert¹, Xin-Chun Huang², Hsin-Yun Hsu³

Affiliations

¹ Institute of Molecular Science, National Chiao-Tung University, No. 1001 Ta-Hsueh Road, Hsinchu 30010, Taiwan.
² Department of Applied Chemistry, National Chiao-Tung University, No. 1001 Ta-Hsueh Road, Hsinchu 30010, Taiwan.
³ Institute of Molecular Science, National Chiao-Tung University, No. 1001 Ta-Hsueh Road, Hsinchu 30010, Taiwan; Department of Applied Chemistry, National Chiao-Tung University, No. 1001 Ta-Hsueh Road, Hsinchu 30010, Taiwan. Electronic address: hyhsu99@nctu.edu.tw.

PMID: 28499603
DOI: 10.1016/j.cis.2017.04.011

Abstract

Silica-based materials have extensive biomedical applications owing to their unique physical, chemical, and biological properties. Recently, increasing studies have examined the mechanisms involved in biosilicification to develop novel, fine-tunable, eco-friendly materials and/or technologies. In this review, we focus on recent developments in bio-templated silica synthesis and relevant applications in drug delivery systems, tissue engineering, and biosensing.

Keywords: Biomolecular template; Biosilica; Composite; Nanoparticle; Silica.

Publication types

Review

MeSH terms

Animals
Biosensing Techniques / methods*
DNA / chemistry
Diatoms / chemistry
Drug Delivery Systems / methods*
Flagella / chemistry
Flagella / ultrastructure
Humans
Mice
Nanoparticles / chemistry
Nanoparticles / ultrastructure
Nanotubes / chemistry
Nanotubes / ultrastructure
Peptides / chemistry
Polysaccharides / chemistry
Silanes / chemistry*
Silicon Dioxide / chemistry*
Tissue Engineering / methods*

Substances

Peptides
Polysaccharides
Silanes
Silicon Dioxide
DNA