Curative Effects for B-Cell Lymphoma Accomplished by Direct-Acting Antiviral Agents of Hepatitis C

Nobuhiro Hattori; Hiroki Ikeda; Hiroyasu Nakano; Nobuyuki Matsumoto; Tsunamasa Watanabe; Ryuta Shigefuku; Yohei Noguchi; Kotaro Matsunaga; Hirotaka Sakai; Chiaki Okuse; Hiroyuki Yamamoto; Ikuo Miura; Michihiro Suzuki; Fumio Itoh

doi:10.1093/ofid/ofx057

Curative Effects for B-Cell Lymphoma Accomplished by Direct-Acting Antiviral Agents of Hepatitis C

Open Forum Infect Dis. 2017 Mar 25;4(2):ofx057. doi: 10.1093/ofid/ofx057. eCollection 2017 Spring.

Affiliations

¹ Divisions of Gastroenterology and Hepatology and.
² Hematology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
³ Division of Gastroenterology and Hepatology, Kawasaki Municipal Tama Hospital, Japan.

Abstract

Hepatitis C virus (HCV) is a hepatotropic and lymphotropic virus with the capabilities of tumorigenesis. We present an HCV-infected patient affected with B-cell lymphomas after suffering from hepatocellular carcinoma. The patient exhibited curative effects for lymphomas after treatment with sofosbuvir and ledipasvir, which is shown clearly with a positron emission tomography scanner.

Keywords: B-cell lymphoma; DAA; FDG-PET/CT.; HCV.