Growth velocity and weight gain in prepubertal asthmatic children

Rev Assoc Med Bras (1992). 2017 Mar;63(3):236-241. doi: 10.1590/1806-9282.63.03.236.

Abstract

Objective:: To evaluate the stature growth rate (GR) and the weight gain of prepubertal asthmatic children.

Method:: A retrospective cohort study evaluating medical records of 85 children diagnosed with asthma, aged less than 9 years, of both sexes, with at least one year of follow-up in the allergy outpatient clinic. The data on the disease, weights and heights were collected through a standardized questionnaire on two occasions, with an interval of one year. The curves proposed by Tanner were applied for the analysis of the GR, and the Z-score of the GR (ZGR) was calculated.

Results:: Excess weight (risk for overweight, overweight and obesity) was observed in 31.8% (27/85) of the patients, but there was no association with the severity of asthma. Low GR (ZGR < -2) was found in 13.9% (11/79) of patients, most frequently among children with moderate/severe persistent asthma compared to persistent mild and intermittent forms (7/11 - 63.6% vs. 21/68 - 30.2%, respectively, p=0.047). Use of steroids (dose, type and time of use) was not associated with GR.

Conclusion:: GR was most affected in children with moderate/severe asthma.

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Age Factors
  • Analysis of Variance
  • Asthma / drug therapy
  • Asthma / physiopathology*
  • Body Height / physiology*
  • Child
  • Child Development / physiology*
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Nutritional Status / physiology
  • Overweight / physiopathology
  • Retrospective Studies
  • Risk Factors
  • Statistics, Nonparametric
  • Time Factors
  • Weight Gain / physiology*

Substances

  • Adrenal Cortex Hormones