Extensions to Multivariate Space Time Mixture Modeling of Small Area Cancer Data

Int J Environ Res Public Health. 2017 May 9;14(5):503. doi: 10.3390/ijerph14050503.

Abstract

Oral cavity and pharynx cancer, even when considered together, is a fairly rare disease. Implementation of multivariate modeling with lung and bronchus cancer, as well as melanoma cancer of the skin, could lead to better inference for oral cavity and pharynx cancer. The multivariate structure of these models is accomplished via the use of shared random effects, as well as other multivariate prior distributions. The results in this paper indicate that care should be taken when executing these types of models, and that multivariate mixture models may not always be the ideal option, depending on the data of interest.

Keywords: disease mapping; incidence; lung and bronchus cancer; melanoma cancer of the skin; mixture model; oral cavity and pharynx cancer; spatio-temporal.

MeSH terms

  • Head and Neck Neoplasms / epidemiology*
  • Humans
  • Lung Neoplasms / epidemiology
  • Melanoma / epidemiology
  • Models, Theoretical
  • Mouth Neoplasms / epidemiology
  • Pharyngeal Neoplasms / epidemiology
  • Small-Area Analysis*
  • Spatio-Temporal Analysis*