Long-Term Impact of Preterm Birth: Neurodevelopmental and Physical Health Outcomes

Clin Perinatol. 2017 Jun;44(2):305-314. doi: 10.1016/j.clp.2017.01.003. Epub 2017 Mar 18.

Abstract

Preterm birth severely disrupts the normal developmental maturation of organ systems, resulting in lasting adverse effects. High blood pressure, cardiac dysfunction, obstructive lung disease, elevated blood glucose, and mental health problems occur earlier and at higher rates in the preterm-born than in the term populations. Disadvantageous health conditions may have a significant impact on the well-being of preterm-born individuals from childhood through adulthood. This review summarizes the impact of preterm birth on neurodevelopment and on cardiovascular, renal, metabolic, and pulmonary health.

Keywords: Cardiovascular diseases; Chronic health diseases; Neurodevelopment; Obstructive lung diseases; Preterm birth.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / epidemiology*
  • Humans
  • Infant, Extremely Premature
  • Infant, Newborn
  • Infant, Premature
  • Insulin Resistance
  • Lung Diseases, Obstructive / epidemiology*
  • Metabolic Syndrome / epidemiology*
  • Neurodevelopmental Disorders / epidemiology*
  • Premature Birth / epidemiology*
  • Renal Insufficiency, Chronic / epidemiology*
  • Time