Acute Respiratory Failure in Patients with Hematologic Malignancies

Anne-Sophie Moreau; Olivier Peyrony; Virginie Lemiale; Lara Zafrani; Elie Azoulay

doi:10.1016/j.ccm.2017.02.001

Acute Respiratory Failure in Patients with Hematologic Malignancies

Clin Chest Med. 2017 Jun;38(2):355-362. doi: 10.1016/j.ccm.2017.02.001.

Authors

Anne-Sophie Moreau¹, Olivier Peyrony², Virginie Lemiale², Lara Zafrani², Elie Azoulay³

Affiliations

¹ Centre de réanimation, Hôpital Salengro, CHU-Lille, Lille F-59000, France.
² Medical Intensive Care Unit, Hôpital Saint-Louis, Paris, France.
³ Medical Intensive Care Unit, Hôpital Saint-Louis, Paris, France. Electronic address: elie.azoulay@sls.aphp.fr.

PMID: 28477644
DOI: 10.1016/j.ccm.2017.02.001

Abstract

Acute respiratory failure occurs in up to 50% of patients treated for hematologic malignancies and is associated with a high case fatality rate. Because of residual organ dysfunction and time spent receiving respiratory care, underlying disease control is affected. Early admission to an intensive care unit for acute respiratory failure has proven benefit because it is the best place for rapid implementation of noninvasive diagnostic and therapeutic strategies. This article reviews the clinical approach and diagnostic strategies for acute respiratory failure in patients with hematologic malignancies.

Keywords: Bronchoalveolar lavage; High-resolution computed tomography; Immunocompromised; Noninvasive tests.

Publication types

Review

MeSH terms

Acute Disease
Female
Hematologic Neoplasms / complications*
Humans
Intensive Care Units
Male
Middle Aged
Respiratory Distress Syndrome / complications*