Pulmonary Toxicities from Conventional Chemotherapy

Paul Leger; Andrew H Limper; Fabien Maldonado

doi:10.1016/j.ccm.2017.01.002

Pulmonary Toxicities from Conventional Chemotherapy

Clin Chest Med. 2017 Jun;38(2):209-222. doi: 10.1016/j.ccm.2017.01.002. Epub 2017 Mar 1.

Authors

Paul Leger¹, Andrew H Limper², Fabien Maldonado³

Affiliations

¹ Division of Internal Medicine, Vanderbilt University Medical Center, T1218 Medical Center North, Nashville, TN 37232-2650, USA.
² Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
³ Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, T1218 Medical Center North, Nashville, TN 37232-2650, USA. Electronic address: fabien.maldonado@vanderbilt.edu.

PMID: 28477634
DOI: 10.1016/j.ccm.2017.01.002

Abstract

Despite significant recent progress in precision medicine and immunotherapy, conventional chemotherapy remains the cornerstone of the treatment of most cancers. Chemotherapy-induced lung toxicity represents a serious diagnostic challenge for health care providers and requires careful consideration because it is a diagnosis of exclusion with significant impact on therapeutic decisions. This review aims to provide clinicians with a valuable guide in assessing their patients with possible chemotherapy-induced lung toxicity.

Keywords: Bronchoscopy; Chemotherapy; Interstitial lung disease; Lung toxicity; Radiation therapy.

Publication types

Review

MeSH terms

Adult
Drug-Related Side Effects and Adverse Reactions / complications*
Humans
Lung Diseases, Interstitial / etiology*
Radiotherapy / adverse effects*
Radiotherapy / methods