Heavy Metal Enlightens Tumor Immunity

Jonathan H Chen; Karin Pelka; Nir Hacohen

doi:10.1016/j.cell.2017.04.017

Heavy Metal Enlightens Tumor Immunity

Cell. 2017 May 4;169(4):567-569. doi: 10.1016/j.cell.2017.04.017.

Authors

Jonathan H Chen¹, Karin Pelka², Nir Hacohen³

Affiliations

¹ Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.
² Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
³ Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address: nhacohen@mgh.harvard.edu.

Abstract

A deep understanding of the immune landscape in human cancer is essential for guiding the development of immunotherapy to benefit more patients with long-lasting efficacy. Now, two studies from Lavin et al. and Chevrier et al. employ mass cytometry to study immune infiltrates in lung adenocarcinoma and clear cell renal cell carcinoma, respectively.

Publication types

Comment

MeSH terms

Carcinoma, Renal Cell / immunology*
Humans
Immunotherapy*
Metals, Heavy

Substances

Metals, Heavy

Abstract

Publication types

MeSH terms

Substances

Grants and funding