Deep brain stimulation (DBS) may be considered in severe cases of therapy-refractory major depressive disorder (MDD). However, DBS for MDD is still an experimental therapy. Therefore, it should only be administered in clinical studies driven by multidisciplinary teams, including surgeons with substantial experience of DBS in the treatment of other conditions.
Keywords: Anorexia nervosa; bed nucleus of the stria terminalis; deep brain stimulation; depression; medial forebrain bundle.