Multiaccess In Vivo Biotelemetry Using Sonomicrometry and M-Scan Ultrasound Imaging

IEEE Trans Biomed Eng. 2018 Jan;65(1):149-158. doi: 10.1109/TBME.2017.2697998. Epub 2017 Apr 25.

Abstract

Objective: In this paper, we investigate the use of commercial off-the-shelf diagnostic ultrasound readers to achieve multiaccess wireless in vivo telemetry with millimeter-sized sonomicrometry crystal transducers.

Methods: The sonomicrometry crystals generate ultrasonic pulses that supersede the echoes generated at the tissue interfaces in response to M-scan interrogation pulses. The traces of these synthetic pulses are captured on an M-scan image and the transmitted data are decoded using image deconvolution and deblurring algorithms.

Results: Using a chicken phantom and 1.3 MHz sonomicrometry crystals of diameter 1 mm, we first demonstrate that a standard ultrasound reader can achieve biotelemetry data rates up to 1 Mb/s for implantation depths greater than 10 cm. For this experiment the maximum power dissipation at the crystals was measured to be 20 and bit-error-rate of the telemetry link was shown to be . We also demonstrate the use of this method for multiaccess biotelemetry where several sonomicrometry crystals simultaneously transmit the data using different modulation and coding techniques. Using a live ovine model, we demonstrate a sonomicrometry crystal implanted in the sheep 's tricuspid valve can maintain a continuous, reliable telemetry link at data rates up tob 800 Kb/s in the presence of respiratory and cardiac motion artifacts.

Conclusion: Compared to existing radio-frequency and ultrasound based biotelemetry devices, the reported data-rates are significantly higher considering the transducer's form-factor and its implantation depth.

Significance: The proposed technique thus validates the feasibility of establishing reliable communication link with multiple in vivo implants using M-scan-based ultrasound imaging.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Animals
  • Chickens
  • Equipment Design
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Muscles / diagnostic imaging
  • Phantoms, Imaging
  • Sheep
  • Signal Processing, Computer-Assisted*
  • Telemetry / methods*
  • Tricuspid Valve / diagnostic imaging
  • Ultrasonography / methods*