What Is Being Measured? A Comparison of Two Depressive Symptom Severity Instruments with a Depression Diagnosis in Low-Income High-Risk Mothers

J Womens Health (Larchmt). 2017 Jun;26(6):683-691. doi: 10.1089/jwh.2016.5974. Epub 2017 Apr 27.

Abstract

Background: Adequate assessment of depressive symptomatology is a necessary step toward decreasing income-related mental health treatment inequity. No studies have focused on comparing instruments used to detect depression in women from low-income backgrounds who are mothers of young children-a period of increased risk for depressive symptoms.

Methods: To address this gap, two commonly used instruments (Center for Epidemiologic Studies Depression Scale [CES-D] and Hamilton Rating Scale for Depression [Hamilton]) were compared with a depression diagnosis (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition [DSM-V]) in a sample (n = 251) of mothers from low-income backgrounds with children ranging from 1 to 54 months old. Diagnostic utility was examined in light of contextual factors associated with maternal depressive symptoms.

Results: In this sample, CES-D had better screening sensitivity and specificity than Hamilton. Our results suggest that Hamilton may underdiagnose cases of major depressive episodes (MDE) as defined by DSM-V among black and low-income mothers compared with CES-D. In addition, we identify items in CES-D, which do not contribute to alignment with DSM-V and are appropriate targets for future improvements. Our analysis identifies interpersonal relationships and mother's age as the primary risk factors, which differentiate between CES-D and Hamilton determinations versus MDE diagnosis. In addition, we find regional differences in CES-D and Hamilton.

Conclusions: It is important to tailor the measure to the context, and a calibration sample should be considered for studies of sufficient size.

Keywords: assessment; depression screening; ethnic/racial minority women; low-income; maternal depression; sensitivity and specificity.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Depression / diagnosis*
  • Depression / psychology
  • Depressive Disorder, Major / diagnosis*
  • Depressive Disorder, Major / psychology
  • Diagnostic and Statistical Manual of Mental Disorders
  • Humans
  • Income
  • Interpersonal Relations
  • Mothers / psychology*
  • Poverty
  • Psychiatric Status Rating Scales*
  • Psychological Tests / standards*
  • Psychometrics / instrumentation*
  • Psychometrics / statistics & numerical data
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Surveys and Questionnaires*