A fuzzy co-clustering algorithm for biomedical data

PLoS One. 2017 Apr 26;12(4):e0176536. doi: 10.1371/journal.pone.0176536. eCollection 2017.

Abstract

Fuzzy co-clustering extends co-clustering by assigning membership functions to both the objects and the features, and is helpful to improve clustering accurarcy of biomedical data. In this paper, we introduce a new fuzzy co-clustering algorithm based on information bottleneck named ibFCC. The ibFCC formulates an objective function which includes a distance function that employs information bottleneck theory to measure the distance between feature data point and the feature cluster centroid. Many experiments were conducted on five biomedical datasets, and the ibFCC was compared with such prominent fuzzy (co-)clustering algorithms as FCM, FCCM, RFCC and FCCI. Experimental results showed that ibFCC could yield high quality clusters and was better than all these methods in terms of accuracy.

MeSH terms

  • Algorithms*
  • Cluster Analysis
  • Databases, Factual

Grants and funding

The authors gratefully acknowledge that this research work was supported by fundings from Natural Science Foundation of China under Frant no. 61202286 (http://www.nsfc.gov.cn/) and Foundation for University Key Teacher by Henan Province under Grant no. 2015GGJS-068(http://www.haedu.gov.cn/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.