A review of drug delivery systems based on nanotechnology and green chemistry: green nanomedicine

Int J Nanomedicine. 2017 Apr 12:12:2957-2978. doi: 10.2147/IJN.S127683. eCollection 2017.

Abstract

This review discusses the impact of green and environmentally safe chemistry on the field of nanotechnology-driven drug delivery in a new field termed "green nanomedicine". Studies have shown that among many examples of green nanotechnology-driven drug delivery systems, those receiving the greatest amount of attention include nanometal particles, polymers, and biological materials. Furthermore, green nanodrug delivery systems based on environmentally safe chemical reactions or using natural biomaterials (such as plant extracts and microorganisms) are now producing innovative materials revolutionizing the field. In this review, the use of green chemistry design, synthesis, and application principles and eco-friendly synthesis techniques with low side effects are discussed. The review ends with a description of key future efforts that must ensue for this field to continue to grow.

Keywords: cancer; drug delivery; green chemistry; nanoparticle.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems / methods*
  • Green Chemistry Technology / methods*
  • Humans
  • Nanomedicine / methods*
  • Nanoparticles / chemistry*
  • Nanotechnology / methods
  • Nanotubes, Carbon / chemistry
  • Plant Extracts / chemistry
  • Polymers / chemistry

Substances

  • Nanotubes, Carbon
  • Plant Extracts
  • Polymers