[Therapy of Hemifacial Spasm with Botulinum Toxin]

Fortschr Neurol Psychiatr. 2017 Apr;85(4):194-198. doi: 10.1055/s-0043-104698. Epub 2017 Apr 24.
[Article in German]

Abstract

Hemifacial spasm (HFS) is a frequent disorder characterized by involuntary contractions of those muscles innervated by the facialis nerve on one side of the face. The symptoms can appear as tonic or clonic, intermittent or permanent. Diagnosis is based purely on clinical observation. Differential diagnosis should rely on cranial MRI, which can demonstrate a pathological contact between the nerves and vessels and exclude alternative causation. Often, the symptoms are not marked so that therapy may not be necessary. The therapy of choice is an injection of botulinum toxin to reduce the underlying pathological activity. As an alternative, decompression operation according to Jannetta can be considered, although it is frequently rejected by patients.

Publication types

  • Review

MeSH terms

  • Anti-Dyskinesia Agents / therapeutic use*
  • Botulinum Toxins / therapeutic use*
  • Hemifacial Spasm / diagnostic imaging
  • Hemifacial Spasm / drug therapy*
  • Hemifacial Spasm / surgery
  • Humans

Substances

  • Anti-Dyskinesia Agents
  • Botulinum Toxins