Short communication: Muscle protein synthetic response to microparticulated whey protein in middle-aged men

J Dairy Sci. 2017 Jun;100(6):4230-4234. doi: 10.3168/jds.2016-12287. Epub 2017 Apr 21.

Abstract

Whey protein concentrate (WPC) is a high-quality dairy ingredient that is often included in formulated food products designed to stimulate muscle anabolism. Whey protein concentrate can be affected by UHT processing, and its sensory properties are not compatible with some formulated food products. Microparticulated WPC (mWPC) is a novel ingredient that is resistant to heat treatment and has enhanced sensory properties. When 16 healthy middle-aged men consumed 20 g of either WPC or mWPC, both proteins increased plasma essential AA and leucine concentrations with no detectable difference in curve kinetics. Myofibrillar protein synthesis was increased in both groups for 90 min after ingestion with no difference between groups. Ingestion of mWPC resulted in a muscle anabolic response that was equivalent to that of WPC over the full 210-min measurement period. Formulated products incorporating mWPC or standard WPC would provoke equivalent anabolic responses.

Keywords: dairy protein; muscle protein turnover; protein concentrate; protein ingredient.

MeSH terms

  • Amino Acids, Essential / blood
  • Anabolic Agents / administration & dosage
  • Anabolic Agents / pharmacokinetics*
  • Animals
  • Food Handling
  • Food, Formulated*
  • Hot Temperature
  • Humans
  • Leucine / blood
  • Male
  • Middle Aged
  • Muscle Proteins / biosynthesis*
  • Time Factors
  • Whey Proteins / administration & dosage
  • Whey Proteins / pharmacology*

Substances

  • Amino Acids, Essential
  • Anabolic Agents
  • Muscle Proteins
  • Whey Proteins
  • Leucine