1H-MRS (proton magnetic resonance spectroscopy) is a method for analyzing material components using the difference of the frequency (chemical shift) in magnetic resonance. 1H-MRS for human body is able to diagnose the clinical conditions by non-invasive analysis of materials in organs. However, the mechanical limitations and complexity in analyses prevented it from becoming popular as MRI (magnetic resonance imaging). Recently, an ideal environment for 1H-MRS is commonly available such as stronger magnetic field and improved software, yet we still lack common knowledges about 1H-MRS which makes whom plans to start it difficult. In this article, the principle, tips, clinical applications and spectrum evaluations were explained focusing on novice users.
Keywords: MRS; brain; chemical shift; liver; metabolite; skeletal muscle.