MethyLock: DNA Demethylation Is the Epigenetic Key to Axon Regeneration

Neuron. 2017 Apr 19;94(2):221-223. doi: 10.1016/j.neuron.2017.04.006.

Abstract

In this issue of Neuron, Weng et al. (2017) reveal a role for active DNA demethylation in allowing axon regeneration to occur in the mature nervous system following axonal injury.

Publication types

  • Review

MeSH terms

  • Animals
  • Axons / metabolism*
  • DNA / metabolism*
  • Epigenomics / methods
  • Gene Expression Regulation / physiology*
  • Humans
  • Nerve Regeneration / physiology*
  • Neurons / metabolism*

Substances

  • DNA