Abstract
Silver(I) complexes of two designed tridentate ligands, namely, 2,6-(pyridyl)iminoditriazaadamantane (pydTAm) and 2,6-(pyridyl)iminodiadamantane (pydAm), have been synthesized and structurally characterized. [Ag(pydTAm)2](CF3SO3) (1), the hitherto unknown mer isomer of a silver(I) octahedral complex, crystallizes in a highly symmetric body-centered cubic I4̅3m space group. Quite in contrast, the AgI center in the analogous [Ag(pydAm)2](CF3SO3) (2) complex resides in a trigonal-bipyramidal geometry and crystallizes in a triclinic P1̅ space group with two crystallographically independent molecules in the asymmetric unit. Complex 1 exhibits exceptional solubility in aqueous media and leads to the efficient eradication of several bacterial strains upon sustained release of bioactive silver.
MeSH terms
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Adamantane / analogs & derivatives*
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Adamantane / chemical synthesis
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Adamantane / chemistry
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Adamantane / pharmacology*
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Anti-Bacterial Agents / chemical synthesis
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology*
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Bacillus subtilis / drug effects
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Coordination Complexes / chemical synthesis
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Coordination Complexes / chemistry
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Coordination Complexes / pharmacology*
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Escherichia coli / drug effects
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Imines / chemical synthesis
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Imines / chemistry
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Imines / pharmacology*
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Isomerism
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Ligands
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Molecular Structure
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Pseudomonas aeruginosa / drug effects
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Pyridines / chemical synthesis
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Pyridines / chemistry
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Pyridines / pharmacology*
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Silver / chemistry
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Silver / pharmacology*
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Solubility
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Staphylococcus epidermidis / drug effects
Substances
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Anti-Bacterial Agents
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Coordination Complexes
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Imines
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Ligands
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Pyridines
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Silver
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Adamantane