Abstract
A novel spiro-indolofuranone fused to a thiazine skeleton, orbicularisine (1), was isolated from gills of the mollusk Codakia orbicularis. The isolation and structure elucidation using spectroscopic evidence including mass and NMR spectroscopy are described. The final structure of 1 was supported by key HMBC correlation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Bivalvia / chemistry*
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Gills / chemistry*
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Indolizines / chemistry
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Indolizines / isolation & purification*
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Indolizines / metabolism
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Spiro Compounds / chemistry
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Spiro Compounds / isolation & purification*
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Spiro Compounds / metabolism
Substances
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Indolizines
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Spiro Compounds
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orbicularisine