Cone-beam computed tomography with automated bone subtraction in preoperative embolization for pelvic bone tumors

PLoS One. 2017 Apr 18;12(4):e0175907. doi: 10.1371/journal.pone.0175907. eCollection 2017.

Abstract

Purpose: To evaluate the usefulness of cone-beam computed tomography with automated bone subtraction (CBCT-ABS) in the preoperative embolization of hypervascular tumors located in the pelvic bone.

Materials and methods: This retrospective study included 26 patients with pelvic bone tumors who underwent preoperative embolization between January 2014 and October 2016. A CBCT-ABS scan was taken in a total of 17 patients (CBCT-ABS group), and only a series of digital subtraction angiographies (DSAs) was taken in the remaining 9 patients (DSA group). The percent devascularization, number of angiographic runs, total dose-area product (DAP), fluoroscopy time, interventional procedure time, operative time, and estimated blood loss were compared between the two groups using Mann-Whitney test.

Results: The percent devascularization, interventional procedure time, fluoroscopy time, operative time, and estimated blood loss were not statistically different between the two groups (p > 0.05). On the other hand, the number of angiographic runs in the CBCT-ABS group was significantly lower than that in the DSA group (p = 0.029). The total DAP of the CBCT-ABS group (mean, 17700.7 μGym2) was higher than that of the DSA group (mean, 8939.4 μGym2) (p = 0.002).

Conclusions: The use of CBCT-ABS during the preoperative embolization of pelvic bone tumors significantly reduces the number of angiographic runs at the cost of an increased radiation dose.

MeSH terms

  • Adult
  • Aged
  • Bone Neoplasms / diagnostic imaging*
  • Bone Neoplasms / therapy
  • Cone-Beam Computed Tomography / economics
  • Cone-Beam Computed Tomography / methods*
  • Embolization, Therapeutic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pelvic Bones / diagnostic imaging*
  • Pelvic Neoplasms / diagnostic imaging*
  • Pelvic Neoplasms / therapy
  • Retrospective Studies

Grants and funding

This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI15C1532), http://www.khidi.or.kr. JW Chung received this fund. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.