Abstract
Among 42 gram-negative bloodstream isolates from inpatients in 3 hospitals in Yangon, Myanmar, admitted during July-December 2014, 16 (38%) were extended-spectrum β-lactamase-producing Enterobacteriaceae and 6 (14%) produced carbapenemase. The high prevalence of multidrug-resistant gram-negative bacteria raises concerns about the empiric treatment of patients with sepsis in Yangon.
Keywords:
CTX-M; ESBL; Enterobacteriaceae; Myanmar; NDM; New Delhi metallo-β-lactamase; Yangon; antimicrobial resistance; bacteria; carbapenem; carbapenemase; extended-spectrum β-lactamase; sepsis; β-lactamase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacteremia*
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Bacterial Proteins / biosynthesis*
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Bacterial Proteins / genetics
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Cross Infection
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Enterobacteriaceae / drug effects
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Enterobacteriaceae / enzymology*
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Enterobacteriaceae / isolation & purification
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Enterobacteriaceae Infections / epidemiology*
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Enterobacteriaceae Infections / microbiology*
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Humans
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Myanmar / epidemiology
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beta-Lactam Resistance
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beta-Lactamases / biosynthesis*
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beta-Lactamases / genetics
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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beta-Lactamases
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carbapenemase