ESBL- and Carbapenemase-Producing Enterobacteriaceae in Patients with Bacteremia, Yangon, Myanmar, 2014

Emerg Infect Dis. 2017 May;23(5):857-859. doi: 10.3201/eid2305.161100.

Abstract

Among 42 gram-negative bloodstream isolates from inpatients in 3 hospitals in Yangon, Myanmar, admitted during July-December 2014, 16 (38%) were extended-spectrum β-lactamase-producing Enterobacteriaceae and 6 (14%) produced carbapenemase. The high prevalence of multidrug-resistant gram-negative bacteria raises concerns about the empiric treatment of patients with sepsis in Yangon.

Keywords: CTX-M; ESBL; Enterobacteriaceae; Myanmar; NDM; New Delhi metallo-β-lactamase; Yangon; antimicrobial resistance; bacteria; carbapenem; carbapenemase; extended-spectrum β-lactamase; sepsis; β-lactamase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacteremia*
  • Bacterial Proteins / biosynthesis*
  • Bacterial Proteins / genetics
  • Cross Infection
  • Enterobacteriaceae / drug effects
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / microbiology*
  • Humans
  • Myanmar / epidemiology
  • beta-Lactam Resistance
  • beta-Lactamases / biosynthesis*
  • beta-Lactamases / genetics

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase