The clinical utility of anthropometric measures to assess adiposity in a cohort of prematurely born infants: Correlations with MRI fat quantification

J Neonatal Perinatal Med. 2017;10(2):133-138. doi: 10.3233/NPM-171657.

Abstract

Objective: To correlate magnetic resonance imaging (MRI) of body fat in preterm infants at the time of hospital discharge with same-day anthropometric measures, and to assess the clinical utility of body mass index (BMI), waist circumference (WC), and WC/length ratio as indicators of visceral fat.

Study design: MRI performed prior to NICU discharge in 25 infants born preterm at <32 weeks gestation. Total body fat and visceral fat were quantified using a commercial software program. The Pearson correlation coefficient (r, 95% C.I.) was used to describe strength of association between MRI fat and anthropometric measures.

Results: BMI and weight at discharge were strongly correlated with total body fat (r = 0.95 and 0.89 respectively; p < 0.001). Total body fat as a % of body weight was moderately correlated with weight (r = 0.53), WC (r = 0.52), and BMI (r = 0.47). Weight, BMI, and ponderal index all were found to correlate with total visceral fat (r = 0.65, 0.64, 0.55 respectively) but WC did not (r = 0.28). WC/length ratio was not correlated with any MRI fat measurements.

Conclusions: BMI and weight at discharge both correlate with MRI fat measurements. Our findings do not support the usefulness of measuring WC or WC/length ratio in preterm infants at term-equivalent age.

Keywords: Anthropometric measures; body mass index; magnetic resonance imaging (MRI); prematurity.

Publication types

  • Observational Study

MeSH terms

  • Adiposity / physiology*
  • Body Mass Index
  • Cohort Studies
  • Female
  • Gestational Age
  • Humans
  • Infant Nutritional Physiological Phenomena
  • Infant, Newborn
  • Infant, Premature*
  • Intensive Care Units, Neonatal
  • Intra-Abdominal Fat / physiology*
  • Magnetic Resonance Imaging*
  • Male
  • Patient Discharge
  • Waist Circumference / physiology*