Airway Clearance Techniques for Primary Ciliary Dyskinesia; is the Cystic Fibrosis literature portable?

Lynne Marie Schofield; Alistair Duff; Cathy Brennan

doi:10.1016/j.prrv.2017.03.011

Airway Clearance Techniques for Primary Ciliary Dyskinesia; is the Cystic Fibrosis literature portable?

Paediatr Respir Rev. 2018 Jan:25:73-77. doi: 10.1016/j.prrv.2017.03.011. Epub 2017 Mar 16.

Authors

Lynne Marie Schofield¹, Alistair Duff², Cathy Brennan³

Affiliations

¹ Leeds Teaching Hospitals, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. Electronic address: lynneschofield@nhs.net.
² Leeds Teaching Hospitals, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. Electronic address: alistair.duff1@nhs.net.
³ Leeds Institute of Health Sciences, University of Leeds, UK. Electronic address: C.A.Brennan@leeds.ac.uk.

PMID: 28408202
DOI: 10.1016/j.prrv.2017.03.011

Abstract

Primary Ciliary Dyskinesia (PCD) is a rare inherited disease with impaired mucociliary clearance. Airway clearance techniques (ACTs) are commonly recommended for patients with PCD to facilitate mucus clearance, despite a lack of evidence in this group. Current physiotherapy practice in PCD is based on evidence extrapolated from the field of Cystic Fibrosis (CF). This paper focuses on the available evidence and outlines challenges in extrapolating evidence between the conditions for best clinical practice.

Keywords: Airway Clearance; CF; Chest Physiotherapy; PCD.

Publication types

Review

MeSH terms

Airway Management / methods*
Child
Cystic Fibrosis / therapy
Humans
Kartagener Syndrome* / physiopathology
Kartagener Syndrome* / therapy
Mucociliary Clearance / physiology
Physical Therapy Modalities*
Treatment Outcome